4I1L

Structural and Biological Features of FOXP3 Dimerization Relevant to Regulatory T Cell Function

4I1L の概要

• エントリーDOI: 10.2210/pdb4i1l/pdb
• 関連するPDBエントリー: 3HSX
• 分子名称: Forkhead box protein P3, SULFATE ION, MAGNESIUM ION, ... (5 entities in total)
• 機能のキーワード: foxp3, dimerization, complex ensemble, stability, regulatory activity, acetyation, dna-binding, metal-binding, nucleus, transcription, zinc-finger, transcription regulator
• 由来する生物種: Mus musculus (mouse)
• 細胞内の位置: Nucleus (Potential): Q99JB6
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 10758.09

構造登録者

Song, X.M.,Greene, M.I.,Zhou, Z.C. (登録日: 2012-11-21, 公開日: 2012-12-05, 最終更新日: 2024-03-20)

• 主引用文献: Song, X.,Li, B.,Xiao, Y.,Chen, C.,Wang, Q.,Liu, Y.,Berezov, A.,Xu, C.,Gao, Y.,Li, Z.,Wu, S.L.,Cai, Z.,Zhang, H.,Karger, B.L.,Hancock, W.W.,Wells, A.D.,Zhou, Z.,Greene, M.I.; Structural and biological features of FOXP3 dimerization relevant to regulatory T cell function.; Cell Rep, 1:665-675, 2012; PubMed: 22813742; DOI: 10.1016/j.celrep.2012.04.012

実験手法

X-RAY DIFFRACTION (2.1 Å)