4HWB
Crystal structure of ectodomain 3 of the IL-13 receptor alpha 1 in complex with a human neutralizing monoclonal antibody fragment
Summary for 4HWB
Entry DOI | 10.2210/pdb4hwb/pdb |
Related | 4HWE |
Descriptor | Interleukin-13 receptor subunit alpha-1, Fab heavy chain, Fab light chain, ... (6 entities in total) |
Functional Keywords | fab, fniii, cytokine signaling, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P78552 |
Total number of polymer chains | 3 |
Total formula weight | 64410.50 |
Authors | |
Primary citation | Redpath, N.T.,Xu, Y.,Wilson, N.J.,Fabri, L.J.,Baca, M.,Andrews, A.E.,Braley, H.,Lu, P.,Ireland, C.,Ernst, R.E.,Woods, A.,Forrest, G.,An, Z.,Zaller, D.M.,Strohl, W.R.,Luo, C.S.,Czabotar, P.E.,Garrett, T.P.,Hilton, D.J.,Nash, A.D.,Zhang, J.G.,Nicola, N.A. Crystal structure of ectodomain 3 of the IL-13 receptor alpha 1 in complex with a human neutralizing monoclonal antibody fragment Biochem.J., 451:165-175, 2013 Cited by PubMed: 23384096DOI: 10.1042/BJ20121819 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.61 Å) |
Structure validation
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