4H3H

Crystal structure of a ternary complex of human symplekin NTD, human Ssu72 and a RNA poymerase II CTD peptide phosphorylated at SER-7

Summary for 4H3H

• Entry DOI: 10.2210/pdb4h3h/pdb
• Related: 3O2Q 4H3K
• Descriptor: Symplekin, RNA polymerase II subunit A C-terminal domain phosphatase SSU72, Pol II CTD peptide, ... (5 entities in total)
• Functional Keywords: heat repeat, phosphatase, rna polymerase ii, hydrolase
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm, cytoskeleton: Q92797; Nucleus: Q9NP77
• Total number of polymer chains: 5
• Total formula weight: 130005.50

Authors

Xiang, K.,Tong, L. (deposition date: 2012-09-13, release date: 2012-10-31, Last modification date: 2017-11-15)

• Primary citation: Xiang, K.,Manley, J.L.,Tong, L.; An unexpected binding mode for a Pol II CTD peptide phosphorylated at Ser7 in the active site of the CTD phosphatase Ssu72.; Genes Dev., 26:2265-2270, 2012; PubMed: 23070812; DOI: 10.1101/gad.198853.112

Experimental method

X-RAY DIFFRACTION (2.2 Å)