4G7V

Crystal structure of voltage sensing domain of Ci-VSP with fragment antibody (R217E, 2.5 A)

Summary for 4G7V

• Entry DOI: 10.2210/pdb4g7v/pdb
• Related: 4G7Y 4G80
• Descriptor: fragment antibody heavy chain, fragment antibody light chain, Voltage-sensor containing phosphatase, ... (7 entities in total)
• Functional Keywords: membrane protein, alpha helix, fragment antibody, voltage sensing domain, sensing voltage
• Biological source: Homo sapiens; More
• Total number of polymer chains: 3
• Total formula weight: 68206.71

Authors

Li, Q. (deposition date: 2012-07-20, release date: 2014-02-05, Last modification date: 2017-12-13)

• Primary citation: Li, Q.,Wanderling, S.,Paduch, M.,Medovoy, D.,Singharoy, A.,McGreevy, R.,Villalba-Galea, C.A.,Hulse, R.E.,Roux, B.,Schulten, K.,Kossiakoff, A.,Perozo, E.; Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain.; Nat. Struct. Mol. Biol., 21:244-252, 2014; PubMed: 24487958; DOI: 10.1038/nsmb.2768

Experimental method

X-RAY DIFFRACTION (2.5 Å)