4G7V

Crystal structure of voltage sensing domain of Ci-VSP with fragment antibody (R217E, 2.5 A)

Summary for 4G7V

Related4G7Y 4G80
Descriptorfragment antibody heavy chain, fragment antibody light chain, Voltage-sensor containing phosphatase, ... (7 entities in total)
Functional Keywordsmembrane protein, alpha helix, fragment antibody, voltage sensing domain, sensing voltage
Biological sourceHomo sapiens
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Total number of polymer chains3
Total molecular weight68206.71
Authors
Li, Q. (deposition date: 2012-07-20, release date: 2014-02-05, Last modification date: 2017-12-13)
Primary citation
Li, Q.,Wanderling, S.,Paduch, M.,Medovoy, D.,Singharoy, A.,McGreevy, R.,Villalba-Galea, C.A.,Hulse, R.E.,Roux, B.,Schulten, K.,Kossiakoff, A.,Perozo, E.
Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain.
Nat. Struct. Mol. Biol., 21:244-252, 2014
PubMed: 24487958 (PDB entries with the same primary citation)
DOI: 10.1038/nsmb.2768
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.5 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.24170.4%1.0%5.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report