4FW0

Structure of rat nNOS heme domain in complex with N(delta)-methyl- N(omega)-hydroxy-L-arginine

Summary for 4FW0

Entry DOI	10.2210/pdb4fw0/pdb
Related	4FVW 4FVX 4FVY 4FVZ
Descriptor	Nitric oxide synthase, brain, PROTOPORPHYRIN IX CONTAINING FE, 5,6,7,8-TETRAHYDROBIOPTERIN, ... (7 entities in total)
Functional Keywords	oxidoreductase, nitric oxide synthase, substrate analog
Biological source	Rattus norvegicus (brown rat,rat,rats)
Cellular location	Cell membrane, sarcolemma ; Peripheral membrane protein : P29476
Total number of polymer chains	2
Total formula weight	99932.47
Authors	Li, H.,Poulos, T.L. (deposition date: 2012-06-29, release date: 2013-05-15, Last modification date: 2023-09-13)
Primary citation	Jansen Labby, K.,Li, H.,Roman, L.J.,Martasek, P.,Poulos, T.L.,Silverman, R.B. Methylated N(omega)-Hydroxy-l-arginine Analogues as Mechanistic Probes for the Second Step of the Nitric Oxide Synthase-Catalyzed Reaction Biochemistry, 52:3062-3073, 2013 Cited by PubMed: 23586781 DOI: 10.1021/bi301571v PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation