4EZ3

CDK2 in complex with NSC 134199

Summary for 4EZ3

• Entry DOI: 10.2210/pdb4ez3/pdb
• Related: 4ERW 4EZ7
• Descriptor: Cyclin-dependent kinase 2, 4-[(E)-(6-hydroxy-2-oxo-1,2-dihydropyridin-3-yl)diazenyl]benzenesulfonamide, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: protein kinase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm, cytoskeleton, centrosome: P24941
• Total number of polymer chains: 1
• Total formula weight: 35117.70

Authors

Alam, R.,Martin, M.,Zhu, J.-Y.,Schonbrunn, E. (deposition date: 2012-05-02, release date: 2012-08-22, Last modification date: 2023-09-13)

• Primary citation: Martin, M.P.,Alam, R.,Betzi, S.,Ingles, D.J.,Zhu, J.Y.,Schonbrunn, E.; A Novel Approach to the Discovery of Small-Molecule Ligands of CDK2.; Chembiochem, 13:2128-2136, 2012; PubMed: 22893598; DOI: 10.1002/cbic.201200316

Experimental method

X-RAY DIFFRACTION (2 Å)