4EMR

Crystal Structure determination of type1 ribosome inactivating protein complexed with 7-methylguanosine-triphosphate at 1.75A

Summary for 4EMR

• Entry DOI: 10.2210/pdb4emr/pdb
• Related: 3MRW
• Descriptor: rRNA N-glycosidase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: 7-mgtp, rip complex, hydrolase
• Biological source: Momordica balsamina (Bitter gourd)
• Total number of polymer chains: 1
• Total formula weight: 28056.37

Authors

Kumar, M.,Kushwaha, G.S.,Sinha, M.,Kaur, P.,Sharma, S.,Singh, T.P. (deposition date: 2012-04-12, release date: 2012-05-02, Last modification date: 2023-11-08)

• Primary citation: Kushwaha, G.S.,Yamini, S.,Kumar, M.,Sinha, M.,Kaur, P.,Sharma, S.,Singh, T.P.; First structural evidence of sequestration of mRNA cap structures by type 1 ribosome inactivating protein from Momordica balsamina.; Proteins, 81:896-905, 2013; PubMed: 23280611; DOI: 10.1002/prot.24248

Experimental method

X-RAY DIFFRACTION (1.75 Å)