4EL1

Crystal structure of oxidized hPDI (abb'xa')

Summary for 4EL1

• Entry DOI: 10.2210/pdb4el1/pdb
• Related: 3UEM 4EKZ
• Descriptor: Protein disulfide-isomerase (2 entities in total)
• Functional Keywords: abb'a' domains, "cghc" active sites, horseshoe shape, enzyme, a redox-regulated chaperone, endoplasmic reticulum, chaperone
• Biological source: Homo sapiens (human)
• Cellular location: Endoplasmic reticulum lumen: P07237
• Total number of polymer chains: 2
• Total formula weight: 108409.77

Authors

Wang, C.,Li, W.,Ren, J.,Ke, H.,Gong, W.,Feng, W.,Wang, C.-C. (deposition date: 2012-04-10, release date: 2013-04-10, Last modification date: 2023-11-08)

• Primary citation: Wang, C.,Li, W.,Ren, J.,Fang, J.,Ke, H.,Gong, W.,Feng, W.,Wang, C.-C.; Structural insights into the redox-regulated dynamic conformations of human protein disulfide isomerase; Antioxid Redox Signal, 19:44-53, 2013; PubMed: 22657537; DOI: 10.1089/ars.2012.4630

Experimental method

X-RAY DIFFRACTION (2.883 Å)