4EBQ

Fab structure of anti-Vaccinia virus D8L antigen mouse IgG2a LA5

Summary for 4EBQ

• Entry DOI: 10.2210/pdb4ebq/pdb
• Related: 2I9L 4E9O
• Descriptor: anti-Vaccinia D8L antigen monoclonal IgG2a antibody LA5, heavy chain, anti-Vaccinia D8L antigen monoclonal IgG2a antibody LA5, light chain, GLYCEROL, ... (7 entities in total)
• Functional Keywords: variable domain, constant domain, cdr, hypervariable region, neutralizing antibody, vaccinia virus, d8l envelope protein, conformational epitope, discontinuous epitope, d8l antigen binding, neutralizing mab in presence of complement, d8l vaccinia envelope protein, papain treatment, immune system
• Biological source: Mus musculus (mouse); More
• Total number of polymer chains: 2
• Total formula weight: 47699.57

Authors

Matho, M.H.,Zajonc, D.M. (deposition date: 2012-03-23, release date: 2012-06-06, Last modification date: 2023-09-13)

• Primary citation: Matho, M.H.,Maybeno, M.,Benhnia, M.R.,Becker, D.,Meng, X.,Xiang, Y.,Crotty, S.,Peters, B.,Zajonc, D.M.; Structural and Biochemical Characterization of the Vaccinia Virus Envelope Protein D8 and Its Recognition by the Antibody LA5.; J.Virol., 86:8050-8058, 2012; PubMed: 22623786; DOI: 10.1128/JVI.00836-12

Experimental method

X-RAY DIFFRACTION (1.6 Å)