4E0S

Crystal Structure of C5b-6

Summary for 4E0S

• Entry DOI: 10.2210/pdb4e0s/pdb
• Descriptor: Complement C5, Complement component C6, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: complement, mac, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 293026.23

Authors

Aleshin, A.E.,Stec, B.,DiScipio, R.,Liddington, R.C. (deposition date: 2012-03-05, release date: 2012-04-18, Last modification date: 2023-09-13)

• Primary citation: Aleshin, A.E.,Discipio, R.G.,Stec, B.,Liddington, R.C.; Crystal structure of c5b-6 suggests structural basis for priming assembly of the membrane attack complex.; J.Biol.Chem., 287:19642-19652, 2012; PubMed: 22500023; DOI: 10.1074/jbc.M112.361121

Experimental method

X-RAY DIFFRACTION (4.21 Å)