4DVA

The crystal structure of human urokinase-type plasminogen activator catalytic domain

Summary for 4DVA

Entry DOI	10.2210/pdb4dva/pdb
Related	2NWN 4DVB 4DW2
Descriptor	Urokinase-type plasminogen activator, SULFATE ION, HEXAETHYLENE GLYCOL, ... (4 entities in total)
Functional Keywords	hydrolase, plasminogen activation, protease, serine protease
Biological source	Homo sapiens (human)
Cellular location	Secreted: P00749
Total number of polymer chains	1
Total formula weight	28472.39
Authors	Jiang, L.,Botkjaer, K.A.,Andersen, L.M.,Yuan, C.,Andreasen, P.A.,Huang, M. (deposition date: 2012-02-23, release date: 2013-01-16)
Primary citation	Jiang, L.,Botkjaer, K.A.,Andersen, L.M.,Yuan, C.,Andreasen, P.A.,Huang, M. Rezymogenation of active urokinase induced by an inhibitory antibody Biochem.J., 449:161-166, 2013 Cited by PubMed: 23016918 DOI: 10.1042/BJ20121132 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.94 Å)

Structure validation