4DGV
Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the broadly neutralizing antibody HCV1, P2(1) form
Summary for 4DGV
Entry DOI | 10.2210/pdb4dgv/pdb |
Related | 4DGY |
Descriptor | HCV1 Heavy Chain, HCV1 Light Chain, E2 peptide, ... (6 entities in total) |
Functional Keywords | immunoglobulin fold, immune system-viral protein complex, immune system/viral protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 49593.40 |
Authors | Kong, L.,Wilson, I.A.,Law, M. (deposition date: 2012-01-26, release date: 2012-05-23, Last modification date: 2023-09-13) |
Primary citation | Kong, L.,Giang, E.,Robbins, J.B.,Stanfield, R.L.,Burton, D.R.,Wilson, I.A.,Law, M. Structural basis of hepatitis C virus neutralization by broadly neutralizing antibody HCV1. Proc.Natl.Acad.Sci.USA, 109:9499-9504, 2012 Cited by PubMed: 22623528DOI: 10.1073/pnas.1202924109 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.805 Å) |
Structure validation
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