4DAG

Structure of the Human Metapneumovirus Fusion Protein with Neutralizing Antibody Identifies a Pneumovirus Antigenic Site

Summary for 4DAG

Entry DOI	10.2210/pdb4dag/pdb
Descriptor	Fusion glycoprotein F0, Neutralizing Antibody DS7 heavy chain, Neutralizing Antibody DS7 light chain, ... (4 entities in total)
Functional Keywords	viral protein, mpv fusion protein, antibody, immune system, ds7 antibody structure, ds7, fab structure, vaccine, viral protein-immune system complex, viral protein/immune system
Biological source	Human metapneumovirus More
Total number of polymer chains	3
Total formula weight	92414.73
Authors	Jardetzky, T.S.,Wen, X. (deposition date: 2012-01-12, release date: 2012-02-29, Last modification date: 2023-09-13)
Primary citation	Wen, X.,Krause, J.C.,Leser, G.P.,Cox, R.G.,Lamb, R.A.,Williams, J.V.,Crowe, J.E.,Jardetzky, T.S. Structure of the human metapneumovirus fusion protein with neutralizing antibody identifies a pneumovirus antigenic site. Nat.Struct.Mol.Biol., 19:461-463, 2012 Cited by PubMed: 22388735 DOI: 10.1038/nsmb.2250 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.3904 Å)

Structure validation