4CY2

Crystal structure of the KANSL1-WDR5-KANSL2 complex.

Summary for 4CY2

• Entry DOI: 10.2210/pdb4cy2/pdb
• Related: 4CY1 4CY3 4CY5
• Descriptor: WD REPEAT-CONTAINING PROTEIN 5, KAT8 REGULATORY NSL COMPLEX SUBUNIT 2, KAT8 REGULATORY NSL COMPLEX SUBUNIT 1, ... (4 entities in total)
• Functional Keywords: transcription, epigenetic regulator, histone acetylation, chromatin
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Nucleus: P61964 Q9H9L4 Q7Z3B3
• Total number of polymer chains: 3
• Total formula weight: 37661.55

Authors

Dias, J.,Brettschneider, J.,Cusack, S.,Kadlec, J. (deposition date: 2014-04-09, release date: 2014-05-14, Last modification date: 2023-12-20)

• Primary citation: Dias, J.,Van Nguyen, N.,Georgiev, P.,Gaub, A.,Brettschneider, J.,Cusack, S.,Kadlec, J.,Akhtar, A.; Structural Analysis of the Kansl1/Wdr5/Kansl2 Complex Reveals that Wdr5 is Required for Efficient Assembly and Chromatin Targeting of the Nsl Complex.; Genes Dev., 28:929-, 2014; PubMed: 24788516; DOI: 10.1101/GAD.240200.114

Experimental method

X-RAY DIFFRACTION (2 Å)