4CY1

Crystal structure of the KANSL1-WDR5 complex.

Summary for 4CY1

Entry DOI	10.2210/pdb4cy1/pdb
Related	4CY2 4CY3 4CY5
Descriptor	WD REPEAT-CONTAINING PROTEIN 5, KAT8 REGULATORY NSL COMPLEX SUBUNIT 1, GLYCEROL, ... (4 entities in total)
Functional Keywords	transcription, epigenetic regulator, histone acetylation, chromatin
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Nucleus: P61964 Q7Z3B3
Total number of polymer chains	4
Total formula weight	72738.53
Authors	Dias, J.,Brettschneider, J.,Cusack, S.,Kadlec, J. (deposition date: 2014-04-09, release date: 2014-05-14, Last modification date: 2023-12-20)
Primary citation	Dias, J.,Van Nguyen, N.,Georgiev, P.,Gaub, A.,Brettschneider, J.,Cusack, S.,Kadlec, J.,Akhtar, A. Structural Analysis of the Kansl1/Wdr5/Kansl2 Complex Reveals that Wdr5 is Required for Efficient Assembly and Chromatin Targeting of the Nsl Complex. Genes Dev., 28:929-, 2014 Cited by PubMed: 24788516 DOI: 10.1101/GAD.240200.114 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation