4C1Q

Crystal structure of the PRDM9 SET domain in complex with H3K4me2 and AdoHcy.

Summary for 4C1Q

Entry DOI	10.2210/pdb4c1q/pdb
Descriptor	HISTONE-LYSINE N-METHYLTRANSFERASE PRDM9, HISTONE H3.1, S-ADENOSYL-L-HOMOCYSTEINE, ... (6 entities in total)
Functional Keywords	transferase-peptide complex, histone methyltransferase, set domain h3k4me3, transferase/peptide
Biological source	MUS MUSCULUS (HOUSE MOUSE) More
Total number of polymer chains	3
Total formula weight	41658.85
Authors	Mathioudakis, N.,Cusack, S.,Kadlec, J. (deposition date: 2013-08-13, release date: 2013-10-16, Last modification date: 2023-12-20)
Primary citation	Wu, H.,Mathioudakis, N.,Diagouraga, B.,Dong, A.,Dombrovski, L.,Baudat, F.,Cusack, S.,De Massy, B.,Kadlec, J. Molecular Basis for the Regulation of the H3K4 Methyltransferase Activity of Prdm9. Cell Rep., 5:13-, 2013 Cited by PubMed: 24095733 DOI: 10.1016/J.CELREP.2013.08.035 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation