4BU2

60S ribosomal protein L27A histidine hydroxylase (MINA53) in complex with Ni(II) and 2-oxoglutarate (2OG)

Summary for 4BU2

Entry DOI	10.2210/pdb4bu2/pdb
Related	2XDV 4BXF 4CCJ 4CCK 4CCM 4CCN 4CCO 4DIQ
Descriptor	BIFUNCTIONAL LYSINE-SPECIFIC DEMETHYLASE AND HISTIDYL-HYDROXYLASE MINA, NICKEL (II) ION, 2-OXOGLUTARIC ACID, ... (5 entities in total)
Functional Keywords	oxidoreductase, non-heme, iron-binding, dsbh, 2-oxoglutarate, dioxygenase, jmjc domain, ribosome biogenesis, nuclear protein, rpl27a, beta-hydroxylation, transcription and epigenetic regulation, signaling
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	51349.18
Authors	Chowdhury, R.,Clifton, I.J.,McDonough, M.A.,Ng, S.S.,Pilka, E.,Oppermann, U.,Schofield, C.J. (deposition date: 2013-06-19, release date: 2014-05-14, Last modification date: 2019-02-06)
Primary citation	Chowdhury, R.,Sekirnik, R.,Brissett, N.C.,Krojer, T.,Ho, C.H.,Ng, S.S.,Clifton, I.J.,Ge, W.,Kershaw, N.J.,Fox, G.C.,Muniz, J.R.C.,Vollmar, M.,Phillips, C.,Pilka, E.S.,Kavanagh, K.L.,von Delft, F.,Oppermann, U.,McDonough, M.A.,Doherty, A.J.,Schofield, C.J. Ribosomal oxygenases are structurally conserved from prokaryotes to humans. Nature, 510:422-426, 2014 Cited by PubMed: 24814345 DOI: 10.1038/nature13263 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.78 Å)

Structure validation