4BKA

crystal structure of the human EphA4 ectodomain in complex with human ephrin A5

Summary for 4BKA

Entry DOI	10.2210/pdb4bka/pdb
Related	4BK4 4BK5 4BKB
Descriptor	EPHRIN TYPE-A RECEPTOR 4, EPHRIN-A5 (2 entities in total)
Functional Keywords	cell adhesion, cell repulsion, receptor clustering, receptor cis interaction, eph-ephrin, eph ectodomain, erythropoetin-producing hepatocellular receptor, lbd, sushi, egf, fn
Biological source	HOMO SAPIENS (HUMAN) More
Total number of polymer chains	2
Total formula weight	83338.93
Authors	Seiradake, E.,Schaupp, A.,del Toro Ruiz, D.,Kaufmann, R.,Mitakidis, N.,Harlos, K.,Aricescu, A.R.,Klein, R.,Jones, E.Y. (deposition date: 2013-04-23, release date: 2013-07-03, Last modification date: 2023-12-20)
Primary citation	Seiradake, E.,Schaupp, A.,Del Toro Ruiz, D.,Kaufmann, R.,Mitakidis, N.,Harlos, K.,Aricescu, A.R.,Klein, R.,Jones, E.Y. Structurally Encoded Intraclass Differences in Epha Clusters Drive Distinct Cell Responses Nat.Struct.Mol.Biol., 20:958-, 2013 Cited by PubMed: 23812375 DOI: 10.1038/NSMB.2617 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (5.3 Å)

Structure validation