4B4S
Crystal Structure of a pro-survival Bcl-2:Bim BH3 complex
Summary for 4B4S
Entry DOI | 10.2210/pdb4b4s/pdb |
Related | 2V6Q 2VM6 2WH6 |
Descriptor | BCL-2-LIKE PROTEIN 10, BCL-2-LIKE PROTEIN 11, TETRAETHYLENE GLYCOL, ... (4 entities in total) |
Functional Keywords | apoptosis |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Mitochondrion: Q9HD36 Endomembrane system; Peripheral membrane protein (By similarity). Isoform BimEL: Mitochondrion. Isoform BimL: Mitochondrion. Isoform BimS: Mitochondrion. Isoform Bim-alpha1: Mitochondrion: O43521 |
Total number of polymer chains | 2 |
Total formula weight | 23112.09 |
Authors | |
Primary citation | Rautureau, G.J.P.,Yabal, M.,Yang, H.,Huang, D.C.S.,Kvansakul, M.,Hinds, M.G. The Restricted Binding Repertoire of Bcl-B Leaves Bim as the Universal Bh3-Only Prosurvival Bcl-2 Protein Antagonist. Cell Death Dis., 3:E443-, 2012 Cited by PubMed: 23235460DOI: 10.1038/CDDIS.2012.178 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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