4AVX

Hepatocyte Growth Factor-Regulated Tyrosine Kinase Substrate (Hgs-Hrs) bound to an IP2 compound at 1.68 A Resolution

Summary for 4AVX

• Entry DOI: 10.2210/pdb4avx/pdb
• Related: 2D3G 3ZYQ
• Descriptor: HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE, 1,2-ETHANEDIOL, ZINC ION, ... (5 entities in total)
• Functional Keywords: signaling protein, structural genomics consortium, sgc, signaling
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Cytoplasm : O14964
• Total number of polymer chains: 1
• Total formula weight: 27015.42

Authors

Williams, E.,Canning, P.,Shrestha, L.,Krojer, T.,Vollmar, M.,Slowey, A.,Conway, S.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Bullock, A. (deposition date: 2012-05-30, release date: 2012-06-13, Last modification date: 2023-12-20)

• Primary citation: Williams, E.,Canning, P.,Shrestha, L.,Krojer, T.,Vollmar, M.,Slowey, A.,Conway, S.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Bullock, A.; Crystal Structure of the Tandem Vhs and Fyve Domains of Hepatocyte Growth Factor-Regulated Tyrosine Kinase Substrate (Hgs-Hrs) Bound to an Ip2 Compound at 1.68 A Resolution; To be Published,

Experimental method

X-RAY DIFFRACTION (1.68 Å)