4YWP
Sucrose Binding Site in genetically engineered Carbonic anhydrase IX
Summary for 4YWP
Entry DOI | 10.2210/pdb4ywp/pdb |
Related | 4ZAO |
Related PRD ID | PRD_900003 |
Descriptor | Carbonic anhydrase 2, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, ZINC ION, ... (4 entities in total) |
Functional Keywords | alpha-carbonic anhydrase, ca ix mimic, sucrose, lyase |
Biological source | Homo sapiens (Human) |
Cellular location | Cytoplasm : P00918 |
Total number of polymer chains | 1 |
Total formula weight | 29252.17 |
Authors | Pinard, M.A.,Aggarwal, M. (deposition date: 2015-03-20, release date: 2015-10-14, Last modification date: 2023-09-27) |
Primary citation | Pinard, M.A.,Aggarwal, M.,Mahon, B.P.,Tu, C.,McKenna, R. A sucrose-binding site provides a lead towards an isoform-specific inhibitor of the cancer-associated enzyme carbonic anhydrase IX. Acta Crystallogr F Struct Biol Commun, 71:1352-1358, 2015 Cited by PubMed: 26457530DOI: 10.1107/S2053230X1501239X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.45 Å) |
Structure validation
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