4Y4P

Crystal structure of the Thermus thermophilus 70S ribosome with rRNA modifications and bound to mRNA and A-, P- and E-site tRNAs at 2.5A resolution

This is a non-PDB format compatible entry.

Summary for 4Y4P

• Entry DOI: 10.2210/pdb4y4p/pdb
• Related: 4Y4O
• Descriptor: 23S Ribosomal RNA, 50S ribosomal protein L14, 50S ribosomal protein L15, ... (60 entities in total)
• Functional Keywords: ribosome, rrna modofications, pseudouridine, rrna methylation, ribosomal protein post-translational modifications, iron-sulfur cluster, beta-thio-aspartate
• Biological source: Escherichia coli; More
• Total number of polymer chains: 112
• Total formula weight: 4571395.35

Authors

Polikanov, Y.S.,Melnikov, S.V.,Soll, D.,Steitz, T.A. (deposition date: 2015-02-10, release date: 2015-03-18, Last modification date: 2019-12-25)

• Primary citation: Polikanov, Y.S.,Melnikov, S.V.,Soll, D.,Steitz, T.A.; Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly.; Nat.Struct.Mol.Biol., 22:342-344, 2015; PubMed: 25775268; DOI: 10.1038/nsmb.2992

Experimental method

X-RAY DIFFRACTION (2.5 Å)