4X1J
X-ray crystal structure of the dimeric BMP antagonist NBL1
Summary for 4X1J
Entry DOI | 10.2210/pdb4x1j/pdb |
Related | 4JPH |
Descriptor | Neuroblastoma suppressor of tumorigenicity 1, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | bmp antagonist, dan family, cystine-knot, bmp binding protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 25749.35 |
Authors | Thompson, T.B.,Nolan, K.,Kattamuri, C. (deposition date: 2014-11-24, release date: 2015-01-14, Last modification date: 2020-07-29) |
Primary citation | Nolan, K.,Kattamuri, C.,Luedeke, D.M.,Angerman, E.B.,Rankin, S.A.,Stevens, M.L.,Zorn, A.M.,Thompson, T.B. Structure of Neuroblastoma Suppressor of Tumorigenicity 1 (NBL1): INSIGHTS FOR THE FUNCTIONAL VARIABILITY ACROSS BONE MORPHOGENETIC PROTEIN (BMP) ANTAGONISTS. J.Biol.Chem., 290:4759-4771, 2015 Cited by PubMed: 25561725DOI: 10.1074/jbc.M114.628412 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
Download full validation report