4WGK
Crystal structure of human neutral ceramidase with Zn-bound phosphate
Summary for 4WGK
Entry DOI | 10.2210/pdb4wgk/pdb |
Descriptor | Neutral ceramidase, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total) |
Functional Keywords | ceramidase, amidase, zinc, phosphate, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 155831.60 |
Authors | Airola, M.V.,Pulkoski-Gross, M.J.,Obeid, L.M.,Hannun, Y.A. (deposition date: 2014-09-18, release date: 2015-07-08, Last modification date: 2023-09-27) |
Primary citation | Airola, M.V.,Allen, W.J.,Pulkoski-Gross, M.J.,Obeid, L.M.,Rizzo, R.C.,Hannun, Y.A. Structural Basis for Ceramide Recognition and Hydrolysis by Human Neutral Ceramidase. Structure, 23:1482-1491, 2015 Cited by PubMed: 26190575DOI: 10.1016/j.str.2015.06.013 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.582 Å) |
Structure validation
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