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4P6F

Crystal structure of the peptolide 12C bound to bacterial ribosome

This is a non-PDB format compatible entry.
Summary for 4P6F
Entry DOI10.2210/pdb4p6f/pdb
Descriptor16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... (59 entities in total)
Functional Keywordsprotein biosynthesis, ribosome, rna, trna, peptide exit tunnel, macrolide, ribosome-ribosome inhibitor complex, ribosome/ribosome inhibitor
Biological sourceThermus thermophilus
More
Total number of polymer chains114
Total formula weight4523029.85
Authors
Fagan, C.E.,Dunham, C.M. (deposition date: 2014-03-24, release date: 2014-10-01, Last modification date: 2023-09-27)
Primary citationWashington, A.Z.,Benicewicz, D.B.,Canzoneri, J.C.,Fagan, C.E.,Mwakwari, S.C.,Maehigashi, T.,Dunham, C.M.,Oyelere, A.K.
Macrolide-Peptide Conjugates as Probes of the Path of Travel of the Nascent Peptides through the Ribosome.
Acs Chem.Biol., 9:2621-2631, 2014
Cited by
PubMed: 25198768
DOI: 10.1021/cb5003224
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.6 Å)
Structure validation

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