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4RUL

Crystal structure of full-length E.Coli topoisomerase I in complex with ssDNA

Summary for 4RUL
Entry DOI10.2210/pdb4rul/pdb
Related3PWT 3PX7
DescriptorDNA topoisomerase 1, single strand DNA, ZINC ION, ... (6 entities in total)
Functional Keywordstopoisomerase 1a, isomerase-dna complex, isomerase/dna
Biological sourceEscherichia coli DH1
More
Total number of polymer chains2
Total formula weight107370.85
Authors
Tan, K.,Chen, B.,Tse-Dinh, Y.C. (deposition date: 2014-11-20, release date: 2015-11-04, Last modification date: 2023-09-20)
Primary citationTan, K.,Zhou, Q.,Cheng, B.,Zhang, Z.,Joachimiak, A.,Tse-Dinh, Y.C.
Structural basis for suppression of hypernegative DNA supercoiling by E. coli topoisomerase I.
Nucleic Acids Res., 43:11031-11046, 2015
Cited by
PubMed: 26490962
DOI: 10.1093/nar/gkv1073
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.9 Å)
Structure validation

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