4PO7
Structure of the Sortilin:neurotensin complex at excess neurotensin concentration
Summary for 4PO7
Entry DOI | 10.2210/pdb4po7/pdb |
Descriptor | Sortilin, Neurotensin/neuromedin N, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | 10 bladed beta-propeller, protein sorting receptor, neurotensin, glycosylation, trans golgi network, protein binding |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 81715.12 |
Authors | Quistgaard, E.M.,Groftehauge, M.K.,Thirup, S.S. (deposition date: 2014-02-25, release date: 2014-07-23, Last modification date: 2020-10-21) |
Primary citation | Quistgaard, E.M.,Grftehauge, M.K.,Madsen, P.,Pallesen, L.T.,Christensen, B.,Srensen, E.S.,Nissen, P.,Petersen, C.M.,Thirup, S.S. Revisiting the structure of the Vps10 domain of human sortilin and its interaction with neurotensin. Protein Sci., 23:1291-1300, 2014 Cited by PubMed: 24985322DOI: 10.1002/pro.2512 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.66 Å) |
Structure validation
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