4NZL
Extracellular proteins of Staphylococcus aureus inhibit the neutrophil serine proteases
Summary for 4NZL
Entry DOI | 10.2210/pdb4nzl/pdb |
Descriptor | Neutrophil elastase, Uncharacterized protein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | primarily beta, serine protease, protease inhibitor, innate immunity, azurophilic granules, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Staphylococcus aureus subsp. aureus More |
Total number of polymer chains | 2 |
Total formula weight | 37506.63 |
Authors | Stapels, D.A.C.,von Koeckritz-Blickwede, M.,Ramyar, K.X.,Bischoff, M.,Milder, F.,Ruyken, M.,Scheepmaker, L.,McWhorter, W.J.,Herrmann, M.,van Kessel, K.P.M.,Geisbrecht, B.V.,Rooijakkers, S.H.M. (deposition date: 2013-12-12, release date: 2014-08-20, Last modification date: 2023-09-20) |
Primary citation | Stapels, D.A.,Ramyar, K.X.,Bischoff, M.,von Kockritz-Blickwede, M.,Milder, F.J.,Ruyken, M.,Eisenbeis, J.,McWhorter, W.J.,Herrmann, M.,van Kessel, K.P.,Geisbrecht, B.V.,Rooijakkers, S.H. Staphylococcus aureus secretes a unique class of neutrophil serine protease inhibitors. Proc.Natl.Acad.Sci.USA, 111:13187-13192, 2014 Cited by PubMed: 25161283DOI: 10.1073/pnas.1407616111 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.85 Å) |
Structure validation
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