4NAB

Structure of the (SR)Ca2+-ATPase mutant E309Q in the Ca2-E1-MgAMPPCP form

Summary for 4NAB

• Entry DOI: 10.2210/pdb4nab/pdb
• Related: 3N8G
• Descriptor: Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, CALCIUM ION, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... (5 entities in total)
• Functional Keywords: mutant e309q, p-type atpase, calcium-transporting atpase, sarcoplasmic reticulum, hydrolase
• Biological source: Oryctolagus cuniculus (European rabbit,Japanese white rabbit,domestic rabbit,rabbits)
• Cellular location: Endoplasmic reticulum membrane ; Multi-pass membrane protein : P04191
• Total number of polymer chains: 1
• Total formula weight: 111088.68

Authors

Bublitz, M.,Clausen, J.D.,Arnou, B.,Montigny, C.,Jaxel, C.,Nissen, P.,Moller, J.V.,Andersen, J.P.,le Maire, M. (deposition date: 2013-10-22, release date: 2013-12-18, Last modification date: 2017-08-09)

• Primary citation: Clausen, J.D.,Bublitz, M.,Arnou, B.,Montigny, C.,Jaxel, C.,Moller, J.V.,Nissen, P.,Andersen, J.P.,le Maire, M.; SERCA mutant E309Q binds two Ca(2+) ions but adopts a catalytically incompetent conformation.; Embo J., 32:3231-3243, 2013; PubMed: 24270570; DOI: 10.1038/emboj.2013.250

Experimental method

X-RAY DIFFRACTION (3.5 Å)