4MN3

Chromodomain antagonists that target the polycomb-group methyllysine reader protein Chromobox homolog 7 (CBX7)

Summary for 4MN3

Entry DOI	10.2210/pdb4mn3/pdb
Descriptor	Chromobox protein homolog 7, peptide, 1,2-ETHANEDIOL, ... (6 entities in total)
Functional Keywords	chromobox domain 7, transcription regulator
Biological source	Homo sapiens (human) More
Cellular location	Nucleus: O95931
Total number of polymer chains	2
Total formula weight	8035.57
Authors	Chakravarthi, S.,Daze, K.,Douglas, S.,Quon, T.,Dev, A.,Peng, F.,Heller, M.,Boulanger, M.J.,Wulff, J.,Hof, F. (deposition date: 2013-09-09, release date: 2014-04-02, Last modification date: 2014-10-08)
Primary citation	Simhadri, C.,Daze, K.D.,Douglas, S.F.,Quon, T.T.,Dev, A.,Gignac, M.C.,Peng, F.,Heller, M.,Boulanger, M.J.,Wulff, J.E.,Hof, F. Chromodomain Antagonists That Target the Polycomb-Group Methyllysine Reader Protein Chromobox Homolog 7 (CBX7). J.Med.Chem., 57:2874-2883, 2014 Cited by PubMed: 24625057 DOI: 10.1021/jm401487x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.542 Å)

Structure validation