4LSU
Crystal structure of broadly and potently neutralizing antibody VRC-PG20 in complex with HIV-1 clade A/E 93TH057 gp120
Summary for 4LSU
Entry DOI | 10.2210/pdb4lsu/pdb |
Related | 3NGB 3SE8 3SE9 4J6R 4JB9 4JPV 4JPW |
Descriptor | HIV-1 CLADE A/E STRAIN 93TH057 GP120, HEAVY CHAIN OF ANTIBODY VRC-PG20, LIGHT CHAIN OF ANTIBODY VRC-PG20, ... (8 entities in total) |
Functional Keywords | neutralizing antibody vrc-pg20, viral protein-immune system complex, viral protein/immune system |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 3 |
Total formula weight | 88848.93 |
Authors | Zhou, T.,Moquin, S.,Kwong, P.D. (deposition date: 2013-07-23, release date: 2013-08-21, Last modification date: 2020-07-29) |
Primary citation | Zhou, T.,Zhu, J.,Wu, X.,Moquin, S.,Zhang, B.,Acharya, P.,Georgiev, I.S.,Altae-Tran, H.R.,Chuang, G.Y.,Joyce, M.G.,Do Kwon, Y.,Longo, N.S.,Louder, M.K.,Luongo, T.,McKee, K.,Schramm, C.A.,Skinner, J.,Yang, Y.,Yang, Z.,Zhang, Z.,Zheng, A.,Bonsignori, M.,Haynes, B.F.,Scheid, J.F.,Nussenzweig, M.C.,Simek, M.,Burton, D.R.,Koff, W.C.,Mullikin, J.C.,Connors, M.,Shapiro, L.,Nabel, G.J.,Mascola, J.R.,Kwong, P.D. Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies. Immunity, 39:245-258, 2013 Cited by PubMed: 23911655DOI: 10.1016/j.immuni.2013.04.012 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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