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4KGQ

Crystal structure of a human light loop mutant in complex with dcr3

Summary for 4KGQ
Entry DOI10.2210/pdb4kgq/pdb
Related3K51 3MHD 3MI8 4EN0 4J6G
DescriptorTumor necrosis factor receptor superfamily member 6B, Tumor necrosis factor ligand superfamily member 14, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywordslight, dcr3, tnf, tnfr, tnf14, structural genomics, psi-biology, new hvem, n-glycosylation, membrane, secreted protein, cytokine, ifn, jelly-roll fold, bind tnf receptor hvem and ltbr, ltbr, protein structure initiative, atoms-to-animals: the immune function network, new york structural genomics research consortium, nysgrc, immune system
Biological sourceHomo sapiens (human)
More
Total number of polymer chains4
Total formula weight74019.27
Authors
Primary citationLiu, W.,Zhan, C.,Cheng, H.,Kumar, P.R.,Bonanno, J.B.,Nathenson, S.G.,Almo, S.C.
Mechanistic basis for functional promiscuity in the TNF and TNF receptor superfamilies: structure of the LIGHT:DcR3 assembly.
Structure, 22:1252-1262, 2014
Cited by
PubMed: 25087510
DOI: 10.1016/j.str.2014.06.013
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.27 Å)
Structure validation

217705

數據於2024-03-27公開中

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