4JGH
Structure of the SOCS2-Elongin BC complex bound to an N-terminal fragment of Cullin5
Summary for 4JGH
Entry DOI | 10.2210/pdb4jgh/pdb |
Descriptor | Suppressor of cytokine signaling 2, Transcription elongation factor B polypeptide 2, Transcription elongation factor B polypeptide 1, ... (4 entities in total) |
Functional Keywords | cullin-ring e3 ubiquitin ligases, ubiquitination, cytosol, ligase |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus (Probable): P62869 P83940 |
Total number of polymer chains | 4 |
Total formula weight | 87878.48 |
Authors | Kim, Y.K.,Kwak, M.J.,Ku, B.,Suh, H.Y.,Joo, K.,Lee, J.,Jung, J.U.,Oh, B.H. (deposition date: 2013-03-01, release date: 2013-08-07, Last modification date: 2023-09-20) |
Primary citation | Kim, Y.K.,Kwak, M.J.,Ku, B.,Suh, H.Y.,Joo, K.,Lee, J.,Jung, J.U.,Oh, B.H. Structural basis of intersubunit recognition in elongin BC-cullin 5-SOCS box ubiquitin-protein ligase complexes. Acta Crystallogr.,Sect.D, 69:1587-1597, 2013 Cited by PubMed: 23897481DOI: 10.1107/S0907444913011220 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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