4G86

Crystal structure of the redox-active cofactor DBMIB bound to the full length circadian clock protein KaiA from Synechococcus elongatus

Summary for 4G86

• Entry DOI: 10.2210/pdb4g86/pdb
• Related: 1R8J
• Descriptor: Circadian clock protein kaiA, 2,5-DIBROMO-3-ISOPROPYL-6-METHYLBENZO-1,4-QUINONE, PENTAETHYLENE GLYCOL, ... (6 entities in total)
• Functional Keywords: homodimer, kaic phosphorylation activator, kaic, protein binding
• Biological source: Synechococcus elongatus
• Total number of polymer chains: 2
• Total formula weight: 67393.20

Authors

Pattanayek, R.,Egli, M. (deposition date: 2012-07-21, release date: 2012-10-24, Last modification date: 2024-02-28)

• Primary citation: Pattanayek, R.,Sidiqi, S.K.,Egli, M.; Crystal Structure of the Redox-Active Cofactor Dibromothymoquinone Bound to Circadian Clock Protein KaiA and Structural Basis for Dibromothymoquinone's Ability to Prevent Stimulation of KaiC Phosphorylation by KaiA.; Biochemistry, 51:8050-8052, 2012; PubMed: 23020633; DOI: 10.1021/bi301222t

Experimental method

X-RAY DIFFRACTION (2.387 Å)