4G5Q

Structure of LGN GL4/Galphai1 complex

4G5Q の概要

• エントリーDOI: 10.2210/pdb4g5q/pdb
• 関連するPDBエントリー: 4G5O 4G5R 4G5S
• 分子名称: Guanine nucleotide-binding protein G(i) subunit alpha-1, G-protein-signaling modulator 2, GUANOSINE-5'-DIPHOSPHATE, ... (6 entities in total)
• 機能のキーワード: galphai, goloco, galpha signaling, asymmetric cell division, cell cycle-signaling protein complex, cell cycle/signaling protein
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Nucleus (By similarity): P63096; Cytoplasm (By similarity): Q8VDU0
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 167504.22

構造登録者

Jia, M.,Li, J.,Zhu, J.,Wen, W.,Zhang, M.,Wang, W. (登録日: 2012-07-18, 公開日: 2012-09-05, 最終更新日: 2024-03-20)

• 主引用文献: Jia, M.,Li, J.,Zhu, J.,Wen, W.,Zhang, M.,Wang, W.; Crystal Structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Galphai subunits in G-coupled heterotrimeric proteins; To be Published,

実験手法

X-RAY DIFFRACTION (2.9 Å)