4DXH

Horse liver alcohol dehydrogenase complexed with NAD+ and 2,2,2-trifluoroethanol

Summary for 4DXH

Entry DOI	10.2210/pdb4dxh/pdb
Related	1HLD 1N92 1P1R 3OQ6 4DWV
Descriptor	Alcohol dehydrogenase E chain, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (ACIDIC FORM), ... (6 entities in total)
Functional Keywords	alcohol dehydrogenase, nad+, trifluoroethanol, michaelis complex rossmann fold, oxidoreductase
Biological source	Equus caballus (domestic horse,equine)
Cellular location	Cytoplasm: P00327
Total number of polymer chains	2
Total formula weight	81967.81
Authors	Plapp, B.V.,Ramaswamy, S. (deposition date: 2012-02-27, release date: 2012-04-11, Last modification date: 2023-09-20)
Primary citation	Plapp, B.V.,Ramaswamy, S. Atomic-Resolution Structures of Horse Liver Alcohol Dehydrogenase with NAD(+) and Fluoroalcohols Define Strained Michaelis Complexes. Biochemistry, 51:4035-4048, 2012 Cited by PubMed: 22531044 DOI: 10.1021/bi300378n PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.12 Å)

Structure validation