4D5N

Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state

Summary for 4D5N

• Entry DOI: 10.2210/pdb4d5n/pdb
• Related: 4D5L 4D5Y 4D61 4D66 4D67 4D68
• EMDB information: 2810
• Descriptor: EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1, CRICKET PARALYSIS VIRUS IRES RNA (2 entities in total)
• Functional Keywords: ribosome-rna complex, crpv ires, ribosome, termination, release factors, ribosome/rna
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Cytoplasm: P62495
• Total number of polymer chains: 2
• Total formula weight: 113404.62

Authors

Muhs, M.,Hilal, T.,Mielke, T.,Skabkin, M.A.,Sanbonmatsu, K.Y.,Pestova, T.V.,Spahn, C.M.T. (deposition date: 2014-11-06, release date: 2015-02-04, Last modification date: 2017-08-30)

• Primary citation: Muhs, M.,Hilal, T.,Mielke, T.,Skabkin, M.A.,Sanbonmatsu, K.Y.,Pestova, T.V.,Spahn, C.M.T.; Cryo-Em of Ribosomal 80S Complexes with Termination Factors Reveals the Translocated Cricket Paralysis Virus Ires.; Mol.Cell, 57:422-, 2015; PubMed: 25601755; DOI: 10.1016/J.MOLCEL.2014.12.016

Experimental method

ELECTRON MICROSCOPY (9 Å)