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4CTZ

Structure of bovine endothelial nitric oxide synthase heme domain in complex with (S)-6-(2-amino-2-(3-(2-(4-methylpyridin-2-yl)ethyl)phenyl)ethyl)-4-methylpyridin-2-amine

Summary for 4CTZ
Entry DOI10.2210/pdb4ctz/pdb
Related4CTP 4CTQ 4CTR 4CTT 4CTU 4CTV 4CTW 4CTX 4CTY 4CU0 4CU1
DescriptorNITRIC OXIDE SYNTHASE, ENDOTHELIAL, PROTOPORPHYRIN IX CONTAINING FE, 5,6,7,8-TETRAHYDROBIOPTERIN, ... (8 entities in total)
Functional Keywordsoxidoreductase, inhibitor complex
Biological sourceBOS TAURUS (CATTLE)
Cellular locationCell membrane : P29473
Total number of polymer chains2
Total formula weight102348.20
Authors
Chreifi, G.,Li, H.,Poulos, T.L. (deposition date: 2014-03-15, release date: 2014-05-07, Last modification date: 2014-12-03)
Primary citationKang, S.,Tang, W.,Li, H.,Chreifi, G.,Martasek, P.,Roman, L.J.,Poulos, T.L.,Silverman, R.B.
Nitric Oxide Synthase Inhibitors that Interact with Both a Heme Propionate and Tetrahydrobiopterin Show High Isoform Selectivity.
J.Med.Chem., 57:4382-, 2014
Cited by
PubMed: 24758147
DOI: 10.1021/JM5004182
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.01 Å)
Structure validation

218500

數據於2024-04-17公開中

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