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4CDC

Human DPP1 in complex with (2S)-2-amino-N-((1S)-1-cyano-2-(4- phenylphenyl)ethyl)butanamide

Summary for 4CDC
Entry DOI10.2210/pdb4cdc/pdb
Related4CDD 4CDE 4CDF
DescriptorDIPEPTIDYL PEPTIDASE 1 EXCLUSION DOMAIN CHAIN, DIPEPTIDYL PEPTIDASE 1 HEAVY CHAIN, DIPEPTIDYL PEPTIDASE 1 LIGHT CHAIN, ... (8 entities in total)
Functional Keywordshydrolase, inhibitor
Biological sourceHOMO SAPIENS (HUMAN)
More
Total number of polymer chains12
Total formula weight162150.76
Authors
Primary citationFurber, M.,Gardiner, P.,Tiden, A.K.,Mete, A.,Ford, R.,Millichip, I.,Stein, L.,Mather, A.,Kinchin, E.,Luckhurst, C.,Barber, S.,Cage, P.,Sanganee, H.,Austin, R.,Chohan, K.,Beri, R.,Thong, B.,Wallace, A.,Oreffo, V.,Hutchinson, R.,Harper, S.,Debreczeni, J.,Breed, J.,Wissler, L.,Edman, K.
Cathepsin C Inhibitors: Property Optimization and Identification of a Clinical Candidate.
J.Med.Chem., 57:2357-, 2014
Cited by
PubMed: 24592859
DOI: 10.1021/JM401705G
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

217705

건을2024-03-27부터공개중

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