4A1G

The crystal structure of the human Bub1 TPR domain in complex with the KI motif of Knl1

Summary for 4A1G

• Entry DOI: 10.2210/pdb4a1g/pdb
• Descriptor: MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1, PROTEIN CASC5 (3 entities in total)
• Functional Keywords: cell cycle, transferase, spindle assembly checkpoint, mitosis, tpr repeat, knl1, kmn network
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Nucleus: O43683 Q8NG31
• Total number of polymer chains: 8
• Total formula weight: 96132.22

Authors

Krenn, V.,Wehenkel, A.,Li, X.,Santaguida, S.,Musacchio, A. (deposition date: 2011-09-15, release date: 2012-02-29, Last modification date: 2023-12-20)

• Primary citation: Krenn, V.,Wehenkel, A.,Li, X.,Santaguida, S.,Musacchio, A.; Structural Analysis Reveals Features of the Spindle Checkpoint Kinase Bub1-Kinetochore Subunit Knl1 Interaction.; J.Cell Biol., 196:451-, 2012; PubMed: 22331848; DOI: 10.1083/JCB.201110013

Experimental method

X-RAY DIFFRACTION (2.6 Å)