3ZJF

A20 OTU domain with irreversibly oxidised Cys103 from 270 min H2O2 soak.

Summary for 3ZJF

• Entry DOI: 10.2210/pdb3zjf/pdb
• Related: 3ZJD 3ZJE 3ZJG
• Descriptor: A20P50, CHLORIDE ION, ... (4 entities in total)
• Functional Keywords: hydrolase, ubiquitin, deubiquitinating enzyme, reversible oxidation, sulphenic acid, cys protease
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Cytoplasm. A20p50: Cytoplasm: P21580 P21580
• Total number of polymer chains: 2
• Total formula weight: 86417.91

Authors

Kulathu, Y.,Garcia, F.J.,Mevissen, T.E.T.,Busch, M.,Arnaudo, N.,Carroll, K.S.,Barford, D.,Komander, D. (deposition date: 2013-01-17, release date: 2013-03-06, Last modification date: 2023-12-20)

• Primary citation: Kulathu, Y.,Garcia, F.J.,Mevissen, T.E.T.,Busch, M.,Arnaudo, N.,Carroll, K.S.,Barford, D.,Komander, D.; Regulation of A20 and Other Otu Deubiquitinases by Reversible Oxidation; Nat.Commun., 4:1569-, 2013; PubMed: 23463012; DOI: 10.1038/NCOMMS2567

Experimental method

X-RAY DIFFRACTION (2.2 Å)