3V00
Studies of a constitutively active G-alpha subunit provide insights into the mechanism of G protein activation.
Summary for 3V00
| Entry DOI | 10.2210/pdb3v00/pdb |
| Descriptor | Guanine nucleotide-binding protein G(t) subunit alpha-1/ Guanine nucleotide-binding protein G(i) subunit alpha-1 chimeric protein, GUANOSINE-5'-DIPHOSPHATE (3 entities in total) |
| Functional Keywords | gtpase, gtp binding, transducer, signal transduction, cell cycle, signaling protein |
| Biological source | Bos taurus (bovine,cow,domestic cattle,domestic cow) More |
| Total number of polymer chains | 3 |
| Total formula weight | 124328.57 |
| Authors | Singh, G.,Cerione, R.A. (deposition date: 2011-12-07, release date: 2012-04-18, Last modification date: 2023-09-13) |
| Primary citation | Singh, G.,Ramachandran, S.,Cerione, R.A. A constitutively active G-alpha subunit provide insights into the mechanism of G protein activation Biochemistry, 51:3232-3240, 2012 Cited by PubMed: 22448927DOI: 10.1021/bi3001984 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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