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3UPO

Structure of penicillin-binding protein A from M. tuberculosis: penicillin G acyl-enzyme complex

Summary for 3UPO
Entry DOI10.2210/pdb3upo/pdb
Related3LO7 3UN7 3UPN 3UPP
DescriptorPenicillin-binding protein A, OPEN FORM - PENICILLIN G (3 entities in total)
Functional Keywordstranspeptidase, peptidoglycan peptide, beta-lactam, penicillin-binding protein-antibiotic complex, penicillin-binding protein/antibiotic
Biological sourceMycobacterium tuberculosis
Cellular locationCell membrane; Single-pass type II membrane protein (Probable): P71586
Total number of polymer chains2
Total formula weight97601.80
Authors
Davies, C.,Fedorovich, A. (deposition date: 2011-11-18, release date: 2012-10-24, Last modification date: 2023-09-13)
Primary citationFedarovich, A.,Nicholas, R.A.,Davies, C.
The role of the beta5-alpha11 loop in the active-site dynamics of acylated penicillin-binding protein A from Mycobacterium tuberculosis
J.Mol.Biol., 418:316-330, 2012
Cited by
PubMed: 22365933
DOI: 10.1016/j.jmb.2012.02.021
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

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