3UHA

Crystal Structure of Saccharopine Dehydrogenase from Saccharomyces cervisiae complexed with NAD.

3UHA の概要

• エントリーDOI: 10.2210/pdb3uha/pdb
• 分子名称: Saccharopine dehydrogenase [NAD+, L-lysine-forming], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, CHLORIDE ION, ... (4 entities in total)
• 機能のキーワード: lysine biosynthesis, proton shuttle, enzyme mechanism, nad binding, oxidoreductase
• 由来する生物種: Saccharomyces cerevisiae (Baker's yeast)
• 細胞内の位置: Cytoplasm: P38998
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 84377.68

構造登録者

Cook, P.F.,Kumar, V.P.,Thomas, L.M.,West, A.H.,Bobyk, K.D. (登録日: 2011-11-03, 公開日: 2012-02-01, 最終更新日: 2023-09-13)

• 主引用文献: Kumar, V.P.,Thomas, L.M.,Bobyk, K.D.,Andi, B.,Cook, P.F.,West, A.H.; Evidence in Support of Lysine 77 and Histidine 96 as Acid-Base Catalytic Residues in Saccharopine Dehydrogenase from Saccharomyces cerevisiae.; Biochemistry, 51:857-866, 2012; PubMed: 22243403; DOI: 10.1021/bi201808u

実験手法

X-RAY DIFFRACTION (2.3 Å)