3U0Z

Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels

3U0Z の概要

関連するPDBエントリー1Q43 3OTF 3U10 3U11
分子名称Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE (3 entities in total)
機能のキーワードhelix, beta sheet, transport protein, cnmp binding
由来する生物種Mus musculus (mouse)
細胞内の位置Membrane; Multi-pass membrane protein O88704
ポリマー鎖数2
分子量合計49720.65
構造登録者
主引用文献
Lolicato, M.,Nardini, M.,Gazzarrini, S.,Moller, S.,Bertinetti, D.,Herberg, F.W.,Bolognesi, M.,Martin, H.,Fasolini, M.,Bertrand, J.A.,Arrigoni, C.,Thiel, G.,Moroni, A.
Tetramerization dynamics of C-terminal domain underlies isoform-specific cAMP gating in hyperpolarization-activated cyclic nucleotide-gated channels.
J.Biol.Chem., 286:44811-44820, 2011
PubMed: 22006928 (主引用文献が同じPDBエントリー)
DOI: 10.1074/jbc.M111.297606
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2.9 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2799011.0%1.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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