3TMP

The catalytic domain of human deubiquitinase DUBA in complex with ubiquitin aldehyde

Summary for 3TMP

• Entry DOI: 10.2210/pdb3tmp/pdb
• Related: 3TMO
• Descriptor: OTU domain-containing protein 5, Polyubiquitin-C (3 entities in total)
• Functional Keywords: otu fold, deubiquitinase, phosphorylation, hydrolase-protein binding complex, hydrolase/protein binding
• Biological source: Homo sapiens (human); More
• Cellular location: Ubiquitin: Cytoplasm (By similarity): P0CG48
• Total number of polymer chains: 8
• Total formula weight: 119269.44

Authors

Ma, X.,Yin, J.,Hymowitz, S.,Starovasnik, M.,Cochran, A. (deposition date: 2011-08-31, release date: 2012-01-11, Last modification date: 2012-02-29)

• Primary citation: Huang, O.W.,Ma, X.,Yin, J.,Flinders, J.,Maurer, T.,Kayagaki, N.,Phung, Q.,Bosanac, I.,Arnott, D.,Dixit, V.M.,Hymowitz, S.G.,Starovasnik, M.A.,Cochran, A.G.; Phosphorylation-dependent activity of the deubiquitinase DUBA.; Nat.Struct.Mol.Biol., 19:171-175, 2012; PubMed: 22245969; DOI: 10.1038/nsmb.2206

Experimental method

X-RAY DIFFRACTION (1.91 Å)