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3TK6

factor Xa in complex with D46-5241

Summary for 3TK6
Entry DOI10.2210/pdb3tk6/pdb
Related1V3X 1WU1 2D1J 2EI6 2EI7 2EI8 3TK5
DescriptorFactor X heavy chain, Factor X light chain, CALCIUM ION, ... (5 entities in total)
Functional Keywordsglycoprotein, hydrolase, serine protease, plasma, blood, coagulation factor, calcium-binding, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (HUMAN)
More
Cellular locationSecreted: P00742 P00742
Total number of polymer chains2
Total formula weight32720.66
Authors
Suzuki, M.,Mochizuki, A.,Nagata, T.,Takano, H.,Kanno, H.,Kishida, M.,Ohta, T. (deposition date: 2011-08-25, release date: 2012-08-29, Last modification date: 2017-11-08)
Primary citationMochizuki, A.,Nagata, T.,Takano, H.,Kanno, H.,Kishida, M.,Suzuki, M.,Ohta, T.
Zwitter ionic potent durable orally active Factor Xa inhibitor.
To be Published,
Experimental method
X-RAY DIFFRACTION (1.8 Å)
Structure validation

217705

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