3T0T
Crystal structure of S. aureus Pyruvate Kinase
Summary for 3T0T
Entry DOI | 10.2210/pdb3t0t/pdb |
Related | 3T05 3T07 |
Descriptor | Pyruvate kinase, N'-[(1E)-1-(1H-benzimidazol-2-yl)ethylidene]-5-bromo-2-hydroxybenzohydrazide, PHOSPHATE ION (3 entities in total) |
Functional Keywords | tetramer, ligand, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Staphylococcus aureus subsp. aureus |
Total number of polymer chains | 4 |
Total formula weight | 263209.04 |
Authors | Worrall, L.J.,Vuckovic, M.,Strynadka, N.C.J. (deposition date: 2011-07-20, release date: 2012-06-06, Last modification date: 2024-02-28) |
Primary citation | Axerio-Cilies, P.,See, R.H.,Zoraghi, R.,Worral, L.,Lian, T.,Stoynov, N.,Jiang, J.,Kaur, S.,Jackson, L.,Gong, H.,Swayze, R.,Amandoron, E.,Kumar, N.S.,Moreau, A.,Hsing, M.,Strynadka, N.C.,McMaster, W.R.,Finlay, B.B.,Foster, L.J.,Young, R.N.,Reiner, N.E.,Cherkasov, A. Cheminformatics-driven discovery of selective, nanomolar inhibitors for staphylococcal pyruvate kinase. Acs Chem.Biol., 7:350-359, 2012 Cited by PubMed: 22066782DOI: 10.1021/cb2003576 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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