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3SZ1

Human PPAR gamma ligand binding domain in complex with luteolin and myristic acid

Summary for 3SZ1
Entry DOI10.2210/pdb3sz1/pdb
Related1PRG 3OM9 3PBA
DescriptorPeroxisome proliferator-activated receptor gamma, nonanoic acid, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one, ... (5 entities in total)
Functional Keywordsppar gamma, nuclear receptor, luteolin, transcription
Biological sourceHomo sapiens (human)
Cellular locationNucleus: P37231
Total number of polymer chains2
Total formula weight64300.81
Authors
Puhl, A.C.,Bernardes, A.,Polikarpov, I. (deposition date: 2011-07-18, release date: 2012-03-21, Last modification date: 2024-02-28)
Primary citationPuhl, A.C.,Bernardes, A.,Silveira, R.L.,Yuan, J.,Campos, J.L.,Saidemberg, D.M.,Palma, M.S.,Cvoro, A.,Ayers, S.D.,Webb, P.,Reinach, P.S.,Skaf, M.S.,Polikarpov, I.
Mode of peroxisome proliferator-activated receptor gamma activation by luteolin.
Mol.Pharmacol., 81:788-799, 2012
Cited by
PubMed: 22391103
DOI: 10.1124/mol.111.076216
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

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